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Development and characterization of monoclonal antibody to the immunoglobulin of turbot (Scophthalmus

Wang Weifang,Li Qingmei,Chai Shujun,Gan Lingling,Hong Lei,Guo Junqing,Lei Jilin

Strategic Study of CAE 2014, Volume 16, Issue 9,   Pages 16-20

Abstract:

Four monoclonal antibodies (mAbs) to immunoglobulin M (IgM) of turbot Scophthalmus maximusIgM reactivity in enzymeindicated that the titre of the mAb was 1:1.024×106 and the minimum detectable amount of IgMResults of immunoblotting showed that the mAb reacted with heavy chain of IgM.The mAbs characterization should prove useful for studying the biology of IgM and its practical application

Keywords: turbot (Scophthalmus     maximus)     immunoglobulin M (IgM)     monoclonal antibody     BALB/C mice    

Development of the expressed immunoglobulin μ chain repertoire during maturation of mice B cells

Jingwen LIANG,Yingfeng LUO,Yi SUN,Meng LEI,Bing ZHANG,Songnian HU,Yaofeng ZHAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 201-213 doi: 10.15302/J-FASE-2014017

Abstract: To gain insight into the shift of the immunoglobulin heavy (IgH) chain repertoire during B cell development

Keywords: repertoire     complementarity determining region 3 of the IgH chain (CDRH3)     immunoglobulin     heavy chain     variable    

A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (

Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3,   Pages 249-259 doi: 10.15302/J-FASE-2015056

Abstract: analyzing transcript data and genome sequences, we conducted a comprehensive analysis of Bactrian camel immunoglobulinPhylogenetic analysis of the constant regions of the camelid immunoglobulin genes indicates that these

Keywords: Bactrian camel     heavy-chain antibodies     VHH     γ3    

DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 507-516 doi: 10.1007/s11684-016-0475-6

Abstract:

Immunoglobulin A nephropathy (IgAN) is a common form of chronic glomerulonephritis with unknown pathogenesis

Keywords: DQB1     human leukocyte antigen (HLA)     IgA nephropathy     haplotype     association study    

Preparation of copolymer-grafted mixed-mode resins for immunoglobulin G adsorption

Shenggang Chen, Tao Liu, Ruiqi Yang, Dongqiang Lin, Shanjing Yao

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 1,   Pages 70-79 doi: 10.1007/s11705-018-1745-4

Abstract: Specially, the copolymer-grafted resins CG-M-A with two functional groups, 5-amino-benzimidazole (ABIThe charge and hydrophobicity of CG-M-A resins could be controlled by manipulating the addition of METACpositive effects together in both protein adsorption and elution: dynamic binding capacity of human ImmunoglobulinG (hIgG) onto CG-M-A resin with the highest ligand ratio of METAC to ABI is 46.8 mg·g at pH 9 and the

Keywords: atom transfer radical polymerization     copolymer-grafting     mixed-mode resin     protein adsorption    

Oral administration of

Sufen ZHAO,Yuanyuan JIA,Weiwei ZHANG,Lili WANG,Yunfei MA,Kedao TENG

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 4,   Pages 318-326 doi: 10.15302/J-FASE-2015080

Abstract: Furthermore, immunoglobulin M- and A-bearing B lymphocytes significantly increased 7 days post infection

Keywords: garlic     infectious bursal disease virus (IBDV)     antiviral effect     IgM-bearing B lymphocyte    

Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 158-173 doi: 10.15302/J-FASE-2014015

Abstract: In this study, we introduced the bovine immunoglobulin μ heavy-chain gene (the orphaned gene on BTA11Bovine IgM was highly expressed in selected transgenic lines, and it largely inhibited rearrangementsof the endogenous immunoglobulin heavy chain (IgH) genes in these lines.The bovine IgM level in the serum was only one-tenth to one-fifth of that of endogenous mouse IgM, suggestingthat most of the serum immunoglobulin were contributed by endogenous IgH gene-expressing B cells.

Keywords: bovine Ig μ heavy-chain     transgenic mice     B cell development     allelic exclusion     immune response     Ig repertoire    

Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review

Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 3,   Pages 465-482 doi: 10.1007/s11705-017-1641-3

Abstract: For more than six decades, chromic acid anodizing (CAA) has been the central process in the surface pre-treatment of aluminum for adhesively bonded aircraft structures. Unfortunately, this electrolyte contains hexavalent chromium (Cr(VI)), a compound known for its toxicity and carcinogenic properties. To comply with the new strict international regulations, the Cr(VI)-era will soon have to come to an end. Anodizing aluminum in acid electrolytes produces a self-ordered porous oxide layer. Although different acids can be used to create this type of structure, the excellent adhesion and corrosion resistance that is currently achieved by the complete Cr(VI)-based process is not easily matched. This paper provides a critical overview and appraisal of proposed alternatives to CAA, including combinations of multiple anodizing steps, pre- and post anodizing treatments. The work is presented in terms of the modifications to the oxide properties, such as morphological features (e.g., pore size, barrier layer thickness) and surface chemistry, in order to evaluate the link between fundamental principles of adhesion and bond performance.

Keywords: aluminum     Cr(VI)-free     surface pre-treatments     anodizing     adhesive bonding    

Scrutiny of non-linear differential equations Euler-Bernoulli beam with large rotational deviation by AGM

M. R. AKBARI,M. NIMAFAR,D. D. GANJI,M. M. AKBARZADE

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 4,   Pages 402-408 doi: 10.1007/s11465-014-0316-8

Abstract:

The kinematic assumptions upon which the Euler-Bernoulli beam theory is founded allow it to be extended to more advanced analysis. Simple superposition allows for three-dimensional transverse loading. Using alternative constitutive equations can allow for viscoelastic or plastic beam deformation. Euler-Bernoulli beam theory can also be extended to the analysis of curved beams, beam buckling, composite beams and geometrically nonlinear beam deflection. In this study, solving the nonlinear differential equation governing the calculation of the large rotation deviation of the beam (or column) has been discussed. Previously to calculate the rotational deviation of the beam, the assumption is made that the angular deviation of the beam is small. By considering the small slope in the linearization of the governing differential equation, the solving is easy. The result of this simplification in some cases will lead to an excessive error. In this paper nonlinear differential equations governing on this system are solved analytically by Akbari-Ganji’s method (AGM). Moreover, in AGM by solving a set of algebraic equations, complicated nonlinear equations can easily be solved and without any mathematical operations such as integration solving. The solution of the problem can be obtained very simply and easily. Furthermore, to enhance the accuracy of the results, the Taylor expansion is not needed in most cases via AGM manner. Also, comparisons are made between AGM and numerical method (Runge-Kutta 4th). The results reveal that this method is very effective and simple, and can be applied for other nonlinear problems.

Keywords: AGM     critical load of columns     large deformations of beam     nonlinear differential equation    

Enhancing power transfer capability through flexible AC transmission system devices: a review

Fadi M. ALBATSH,Saad MEKHILEF,Shameem AHMAD,H. MOKHLIS,M. A. HASSAN

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 8,   Pages 658-678 doi: 10.1631/FITEE.1500019

Abstract: Global demand for power has significantly increased, but power generation and transmission capacities have not increased proportionally with this demand. As a result, power consumers suffer from various problems, such as voltage and frequency instability and power quality issues. To overcome these problems, the capacity for available power transfer of a transmission network should be enhanced. Researchers worldwide have addressed this issue by using flexible AC transmission system (FACTS) devices. We have conducted a comprehensive review of how FACTS controllers are used to enhance the available transfer capability (ATC) and power transfer capability (PTC) of power system networks. This review includes a discussion of the classification of different FACTS devices according to different factors. The popularity and applications of these devices are discussed together with relevant statistics. The operating principles of six major FACTS devices and their application in increasing ATC and PTC are also presented. Finally, we evaluate the performance of FACTS devices in ATC and PTC improvement with respect to different control algorithms.

Keywords: FACTS devices     Available transfer capability     Power transfer capability     Artificial intelligence    

Combined heat and power plant integrated with mobilized thermal energy storage (M-TES) system

M, Erik DAHLQUIST

Frontiers in Energy 2010, Volume 4, Issue 4,   Pages 469-474 doi: 10.1007/s11708-010-0123-9

Abstract: The mobilized thermal energy storage (M-TES) system is an alternative source of heat for detached buildingsIn this paper, the integration of a combined heat and power (CHP) plant and an M-TES system is analyzedThe performance of the M-TES system is likewise discussed.

Keywords: Mobilized thermal energy system     district heating     thermal energy storage     combined heat and power     detached houses    

The Deep Carbon Observatory: A Ten-Year Quest to Study Carbon in Earth

Craig M. Schiffries, Andrea Johnson Mangum, Jennifer L. Mays, Michelle Hoon-Starr, Robert M. Hazen

Engineering 2019, Volume 5, Issue 3,   Pages 372-378 doi: 10.1016/j.eng.2019.03.004

ThMn12-Type Alloys for Permanent Magnets Review

Hadjipanayis, A.M. Gabay, A.M. Schönhöbel, A. Martín-Cid, J.M. Barandiaran, D. Niarchos

Engineering 2020, Volume 6, Issue 2,   Pages 140-146 doi: 10.1016/j.eng.2018.12.011

Abstract:

Iron-rich compounds with the tetragonal ThMn12-type structure have the potential to meet current demands for rare-earth-lean permanent magnets with high energy density and operating temperatures of 150–200 ℃. However, while it is normal for magnet technology to lag behind the development of underlying magnetic material, this gap has always been unusually large for ThMn12-type magnets. The gap has widened further in recent years, as excellent combinations of intrinsic magnetic properties have been obtained in compounds synthesized with a smaller amount of structure-stabilizing elements (e.g., SmFe11V or Sm0.8Zr0.2Fe9.2Co2.3Ti0.5) or with no such elements (i.e., SmFe9.6Co2.4 thin films). The search for promising compounds continues—with increasing help coming from theoretical calculations. Unfortunately, progress in the development of magnets beyond polymer-bonded interstitially modified powders remains marginal. The introduction of lanthanum (La) was found to stabilize low-meltingtemperature minority phases in Sm(Fe,Ti)12 alloys, thus allowing for liquid-phase sintering for the first time. The high reactivity of La, however, has apparently undermined the development of coercivity (Hc). A controlled crystallization of the initially suppressed ThMn12-type phase makes "bulk" magnetic hardening possible, not only in Sm-Fe-V alloys (in which it has been known since the 1990s), but also is in La-added (Ce,Sm)(Fe,Ti)12 alloys. The properties of the bulk-hardened alloys, however, remain unsatisfactory. Mechanochemically synthesized (Sm,Zr)(Fe,Si)12 and (Sm,Zr)(Fe,Co,Ti)12 powders may become suitable for sintering into powerful fully dense magnets, although not before a higher degree of anisotropy in both alloys and a higher Hc in the latter alloy have been developed.

Keywords: Permanent magnets     Rare earths permanent magnets     ThMn12 structure    

Velocity gradient elasticity for nonlinear vibration of carbon nanotube resonators

Hamid M. SEDIGHI, Hassen M. OUAKAD

Frontiers of Structural and Civil Engineering 2020, Volume 14, Issue 6,   Pages 1520-1530 doi: 10.1007/s11709-020-0672-x

Abstract: In this study, for the first time, we investigate the nonlocality superimposed to the size effects on the nonlinear dynamics of an electrically actuated single-walled carbon-nanotube-based resonator. We undertake two models to capture the nanostructure nonlocal size effects: the strain and the velocity gradient theories. We use a reduced-order model based on the differential quadrature method (DQM) to discretize the governing nonlinear equation of motion and acquire a discretized-parameter nonlinear model of the system. The structural nonlinear behavior of the system assuming both strain and velocity gradient theories is investigated using the discretized model. The results suggest that nonlocal and size effects should not be neglected because they improve the prediction of corresponding dynamic amplitudes and, most importantly, the critical resonant frequencies of such nanoresonators. Neglecting these effects may impose a considerable source of error, which can be amended using more accurate modeling techniques.

Keywords: velocity gradient elasticity theory     nanotube resonators     differential-quadrature method     nonlinear vibration    

RNA m6A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 481-489 doi: 10.1007/s11684-018-0654-8

Abstract:

N6-methyladenosine (m6A) is the most common post-transcriptional RNAmodification throughout the transcriptome, affecting fundamental aspects of RNA metabolism. m6A modification could be installed by m6A “writers” composed of core catalyticThe function of m6A is executed by m6A “readers” that bind to mm6A are still largely unknown.

Keywords: RNA modification     m6A     immunity     cancer     epigenetics    

Title Author Date Type Operation

Development and characterization of monoclonal antibody to the immunoglobulin of turbot (Scophthalmus

Wang Weifang,Li Qingmei,Chai Shujun,Gan Lingling,Hong Lei,Guo Junqing,Lei Jilin

Journal Article

Development of the expressed immunoglobulin μ chain repertoire during maturation of mice B cells

Jingwen LIANG,Yingfeng LUO,Yi SUN,Meng LEI,Bing ZHANG,Songnian HU,Yaofeng ZHAO

Journal Article

A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (

Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN

Journal Article

DQB1*060101 may contribute to susceptibility to immunoglobulin A nephropathy in southern Han Chinese

Wei Wang,Ming Li,Li Wang,Xueqing Yu

Journal Article

Preparation of copolymer-grafted mixed-mode resins for immunoglobulin G adsorption

Shenggang Chen, Tao Liu, Ruiqi Yang, Dongqiang Lin, Shanjing Yao

Journal Article

Oral administration of

Sufen ZHAO,Yuanyuan JIA,Weiwei ZHANG,Lili WANG,Yunfei MA,Kedao TENG

Journal Article

Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

Journal Article

Towards Cr(VI)-free anodization of aluminum alloys for aerospace adhesive bonding applications: A review

Abrahami, John M. M. de Kok, Herman Terryn, Johannes M. C. Mol

Journal Article

Scrutiny of non-linear differential equations Euler-Bernoulli beam with large rotational deviation by AGM

M. R. AKBARI,M. NIMAFAR,D. D. GANJI,M. M. AKBARZADE

Journal Article

Enhancing power transfer capability through flexible AC transmission system devices: a review

Fadi M. ALBATSH,Saad MEKHILEF,Shameem AHMAD,H. MOKHLIS,M. A. HASSAN

Journal Article

Combined heat and power plant integrated with mobilized thermal energy storage (M-TES) system

M, Erik DAHLQUIST

Journal Article

The Deep Carbon Observatory: A Ten-Year Quest to Study Carbon in Earth

Craig M. Schiffries, Andrea Johnson Mangum, Jennifer L. Mays, Michelle Hoon-Starr, Robert M. Hazen

Journal Article

ThMn12-Type Alloys for Permanent Magnets

Hadjipanayis, A.M. Gabay, A.M. Schönhöbel, A. Martín-Cid, J.M. Barandiaran, D. Niarchos

Journal Article

Velocity gradient elasticity for nonlinear vibration of carbon nanotube resonators

Hamid M. SEDIGHI, Hassen M. OUAKAD

Journal Article

RNA m6A modification and its function in diseases

Jiyu Tong, Richard A. Flavell, Hua-Bing Li

Journal Article